2024-08-15 09:26:31
Biology
Genetics
Science
Decoding the South American Lungfish Genome
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t-online
The genome of the South American lungfish, which is 30 times larger than the human genome, contains over 90% autonomous transposons that replicate rapidly. Comparison with the Australian lungfish shows that its limb-like fins have regressed into threadlike fins in the present-day representatives in South America and Africa. Furthermore, the analyses show that the development of the lung and the formation of fingers, ulna and radius in lungfish and humans are based on the same genes. The South..
heise online
Decoding the DNA of the Lungfish: 30 Times Larger than the Human Genome | heise online
The massive genome of the South American lungfish, 30 times larger than the human genome, grows extremely quickly through active transposons, but shows remarkable stability. Comparisons with other species provide insights into the evolution from aquatic to terrestrial life 400 million years ago and the connection between fin rays and fingers. Experiments with CRISPR-Cas transgenic mice show that changes in the Shh signaling pathway can explain the simplification of the fins.
heise online
Deciphering the DNA of the lungfish: 30 times larger than the human genome | heise online
An international team of researchers has deciphered the largest known animal genome to date - that of the South American lungfish (Lepidosiren paradoxa), which is 30 times larger than the human genome. The results promise insights into the transition from aquatic to terrestrial life of the ancestors of today's land vertebrates.
n-tv.de
30 Times Larger Than Humans: Prehistoric Fish Has the Largest Genome of All Animals - n-tv.de
The South American lungfish has the largest known genome of all animals, 30 times larger than that of humans; Lungfish are considered the closest relatives of the ancestors of today's terrestrial vertebrates; Comparisons of the genomes of different lungfish species allow conclusions to be drawn about the evolution of limbs and lungs.
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